When getting into post processing after having been converted to a RAW shooter years ago I first used View NX2 and Capture NX2, because it was recommended to me. Reason was that the Nikon algorithms to process their own RAW format were and still are considered superior to third party products by many phtographers out there, especially compared to the Adobe software. After getting my D750 I could not use the discontinued Nikon software anymore and swithced to Capture NX-D, where Iwas missing the selective post processing functions of NX2 for occasional tweaking of particular details in some photos. After I learned here in the forum that Capture One uses the Nikon algorithms - at least in the Nikon only version, I tried C1 for the 30 days and then got a subscription a couple of days ago. After taking my first days practicing I see no reason to go for an Adobe product and I must admit that this company has driven me nuts a couple of times in the past in relation to my job. Thus I made it a principle not to use any of their software, being it PDF stuff, photography or whatever...
As I was used to work without catalogues, sessions etc. I stay with this approach and use C1 just for processing the NEFs and exporting them to JPG. Everything else like tagging, shrinking etc. I do with XnViewMP, which is great from its functions and because it is a PortableApp, i.e. runs without installation. So I can have it on an SSD together with my photos and it will run on any PC where I plug in the SSD.
Currently I am not using plug-ins. I tested Topaz DeNoise and I realized that there is the same detour via auxiliary file formats like TIFFs that I had to take when using Capture NX2 as a plug-in to Capture NX-D to be able to occasionally use its selective processing tools. But I didn't like that. At the moment I am still trying to get in the new software and before I haven't learned to use its functionality properly I will not be ble to tell whether the denoise functions in there are sufficient for me or not. Once I get to a point that they are not, I will think about plug-ins again.