This may go against the grain but my wife and I have considered this for some time. Here is where we netted out. A travel trailer and truck to haul it would end up being north of 100,000 USD by the time all was said and done. A Motorhome would be that much or more and we would need to haul an automobile to drive around in once we reached the destination. Saying an average night in a motel is $150, that would be over 650 hotel nights before we broke even without even considering the cost for campgrounds, hookups, maintenance on the trailer or motorhome etc.
We could spend a whole lot of time in motels before ever breaking even. Yes, with motorhomes we may be able to get closer to where we wanted to photograph but in reality, one still has to drive to a trail head and then hike.
Another drawback to the "van life" or "camper life" is how much togetherness can a happily married couple endure and remain happily married?
Leslie and I have been married for 40 years this year. She has her things to do, I have my things to do, and we have our things to do. One of the "our" things is nature and wildlife photography. She is my partner and I cherish every minute on the trail with her. As much as I love her (and I do with all my heart and mind) I'm not sure I would want to spend every waking and sleeping minute with her in a camper or motorhome. I would be afraid she would strangle me in my sleep after a couple months. At the risk of being overly crude, between flatus attacks, bowel movements, snoring (even with CPAP) and various other bodily sounds, I am not the most easy person to live with. I won't talk about her various sounds and smells because we all know wives have none of those issues (or so the ladies will try to convince us).
For these reasons we've decided to drive to our photo destinations, sleep on soft beds, eat in restaurants, and pack picnic lunches and breakfasts for the days afield. We spend 3-5 days per week year around in the field with our cameras. Many of those are within an hour drive from home but several times a year we go on a trip to photograph wildlife and nature. Nature photography is our passion and I'm a fortunate man to have a life partner who shares the same passion as I do.
Hope this helps. I don't want to be "Debbie downer" on this and if it's something you want to do, great, go for it and don't look back. I'm just trying to add a little different perspective.
Jeff (and Leslie).