Makes sense ... However, forgive me:
A combination of both XQD and CFExpress does not seem to be possible on my D850. Were there different configurations for the D850 over time, or are you referring to a different camera model? (My D850 allows for one XQD or CFExpress, plus one SD card, FWIW.)
Sorry about my confusing wording. You can use either XQD or CFExpress in the larger slot, and SD in the smaller slot. My comment referred to using a mix of either an XQD or CFExpress card in that slot. I've stopped using XQD cards and readers so I could simply limit my memory cards to CFExpress cards and reader and SD. That means I don't need to carry both XQD and CFExpress readers.
This discussion has been just about XQD and CFExpress. For test purposes, I removed the SD card. I've heard some reports that having an SD card in the camera for overflow may slow write speed when you were just using the XQD/CFExpress card slot, but I did not verify that in my testing.