Pro wildlife photographers like
@Steve and pro portrait photographers like Matt Granger have reported that they see no useful difference between HE* and Lossless compressed raw.
I shoot a lot of birds for ID in a wide range of lighting conditions and ISO from 64 to 2500 and rarely up to 8 to 10,000.
So far I can not tell any difference between the lossless compressed and HE*.
Like
@Steve I have still used lossless compressed most of the time until the last few weeks. I have switched for the last 3 shoots to HE* since I prefer the smaller file storage size.
And my hardware all works well with HE*
I use Delkin Black CFexpress b and process on an Apple M1Max Studio with 27" studio display and keep my images and LRC catalog on a OWC Envoy Pro SX w/thunderbolt OWCTB3ENVPSX04 4TB and back up with carbon copy cloner to 3 other external SSD drives.