The 500 PF is a big step up in AF and sharpness from the Tammy 150-600 in my experience. If you can stand the hit to your pocketbook, I highly recommend the 500 PF.
That said, if you want light weight and very good sharpness and are okay with the shorter focal length, the 300 PF is a really sweet little lens.
That said, if you want light weight and very good sharpness and are okay with the shorter focal length, the 300 PF is a really sweet little lens.