The internal zoom is certainly a plus. The 100-400 zoom is not a nice mechanism in my opinion. The tight setting isn't tight enough and the loose setting isn't loose enough and the throw to go 100 to 400 is too long.
As far as macroesk, the 70-200 has 0.3x at 40cm at 200mm where as the 100-400 has 0.35x at 98cm. But if you throw a 2xTC on the 70-200 then it will be 0.6x at 40cm so a lot more macro than the 100-400. Of course you can throw TCs on the 100-400 and get up to 0.7x at 98cm at 800mm. Although I never really found the 100-400/2x to pair that well. I think the 70-200II is now just as good as a semi-macro lens as the 100-400. I think the 100-400 benefit is a very nice 560 f/8 lens where as the 70-200 maxes at 400 and I'm really not convinced if the 2xTC is going to produce an image anywhere near the bare 100-400 at 400.
Here is the Digital Picture MM/MFD chart for those two lenses and others in that range:
View attachment 34957
Also if you compare the IQ at 400mm of these two lenses the 100-400 is noticeably better than 70-200/2x in the TDP charts:
https://www.the-digital-picture.com...eraComp=1106&SampleComp=0&FLIComp=4&APIComp=0