Thread locker is no replacement for proper torque on the screws. It will help keep screws from vibrating out or in use cases where a lot of stress may be placed on the screws.
I would check with RRS to see what the torque spec is for the screws. Get a torque screwdriver, set it to the inch pound specs from RRS and you should be fine. Lots of things you can do to help with backing out. A small star or lock washer, a rubber washer between the parts and, of course, Locktite. But the best course would be to properly torque the screws and check for proper tightness from time to time.
Jeff